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CURE Childhood Cancer
How can we stop leukemia from becoming resistant to treatment? Some of the most aggressive childhood leukemias are drive
CURE Childhood CancerSeptember 11, 2026

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How can we stop leukemia from becoming resistant to treatment?

Some of the most aggressive childhood leukemias are driven by changes in a gene called KMT2A. While newer drugs called menin inhibitors have shown promising results, leukemia cells can sometimes find ways to keep growing despite treatment. Dr. Resar’s research focuses on a protein called HMGA1, which appears to help leukemia cells survive even when these drugs are working. Her team is studying how HMGA1 causes treatment resistance and identifying existing drugs that could help restore the effectiveness of therapy. Learn more about her research on our website. #CUREChildhoodCancer #ChildhoodCancerAwarenessMonth #ChildhoodCancerAwareness #ChildhoodCancerResearch #ChildhoodLeukemia
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